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PMID: 4362518 Published · ppublish English Journal Article

Comparison of 6-94 virus and Sendai virus RNA by RNA-RNA hybridization.

Journal of virology ·Vol. 13 ·No. 4 ·1974-04-00 ·Pages 935-6

Kolakofsky D, Spahr PF, Koprowski H

Abstract

The genomic RNA of 6/94 virus, an agent isolated from the brains of multiple sclerosis patients, was studied for sequence homology by RNA-RNA hybridization with closely related Sendai virus and another paramyxovirus virus, Newcastle disease virus. It was found that the genomic RNA of 6/94 virus hybridizes equally as well to the virus-specific 18S RNA found in Sendai-infected cells as that of Sendai virus.

MeSH Terms
Humans Multiple Sclerosis/microbiology Newcastle disease virus/analysis Nucleic Acid Hybridization Parainfluenza Virus 1, Human/analysis Paramyxoviridae/analysis RNA, Viral/analysis
Chemicals
RNA, Viral
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Kolakofsky D
Spahr P F
Koprowski H
References (3)
3 references, click to expand
  1. Replication of Sendai virus. I. Comparison of the viral RNA and virus-specific RNA synthesis with Newcastle disease virus.
    Virology. 1968 Aug;35(4):537-49 PMID: 4300362
  2. Morphogenesis and structure of a virus in cells cultured from brain tissue from two cases of multiple sclerosis.
    Lab Invest. 1973 Apr;28(4):494-500 PMID: 4634094
  3. Molecular weight determination of Sendai RNA by dimethyl sulfoxide gradient sedimentation.
    J Virol. 1973 May;11(5):615-20 PMID: 4350707
Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
Published
1974-04-00
Pages
935-6
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC355393
Subset
IM
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