Location of the origin of DNA replication in adenovirus Type 2.

Journal of virology ·Vol. 13 ·No. 5 ·1974-05-00 ·Pages 1046-54

Horwitz MS

Abstract

Utilizing the isolated left and right halves of both adenovirus type 2 and the nondefective adenovirus simian virus 40 hybrid (Ad2(+)ND(1)), studies were undertaken to find the site on the DNA molecules at which replication begins. The data are consistent with several models which include an initiation event at both ends and bidirectional growth.

MeSH Terms

Adenoviridae Centrifugation, Density Gradient DNA Replication DNA, Single-Stranded DNA, Viral Models, Chemical Nucleic Acid Hybridization Simian virus 40 Thymidine Tritium

Chemicals

DNA, Single-Stranded DNA, Viral Tritium Thymidine

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Horwitz M S

References (20)

20 references, click to expand

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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.13.5.1046-1054.1974

Published

1974-05-00

Pages

1046-54

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC355413

Subset

External Links

PubMed source DOI: 10.1128/JVI.13.5.1046-1054.1974 PMC Full Text View journal details

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Location of the origin of DNA replication in adenovirus Type 2.

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