Thyrotropin-binding properties of isolated thyroid cells and their purified plasma membranes. Relation of thyrotropin-specific binding to adenylate-cyclase activation.

Adenylyl Cyclases/metabolism Animals Binding Sites Bucladesine/pharmacology Cell Membrane/drug effects,metabolism Cells, Cultured Centrifugation, Density Gradient Chromatography, Gel Electrophoresis, Polyacrylamide Gel Enzyme Activation Iodine Radioisotopes Kinetics Mathematics Microscopy, Electron Phosphorus Radioisotopes Protein Binding Receptors, Cell Surface Swine Thyroid Gland/cytology,drug effects,metabolism Thyrotropin/metabolism,pharmacology

Iodine Radioisotopes Phosphorus Radioisotopes Receptors, Cell Surface Bucladesine Thyrotropin Adenylyl Cyclases