Receptor-binding assay of chemically modified insulins. Comparison with in vitro and in vivo bioassays.

Diabetologia ·Vol. 10 ·No. 1 ·1974-02-00 ·Pages 1-5

Freychet P, Brandenburg D, Wollmer A

Abstract

暂无摘要

MeSH Terms

Animals Binding Sites Biological Assay Cell Membrane/metabolism Chemistry, Organic Circular Dichroism Cross Reactions In Vitro Techniques Insulin/metabolism Iodine Radioisotopes Liver/metabolism Organic Chemistry Phenomena Proinsulin/metabolism Protein Binding Receptors, Cell Surface Structure-Activity Relationship Swine

Chemicals

Insulin Iodine Radioisotopes Receptors, Cell Surface Proinsulin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Freychet P

Brandenburg D

Wollmer A

References (13)

13 references, click to expand

The effect of a non-peptide interchain crosslink on the reoxidation of reduced insulin.
Hoppe Seylers Z Physiol Chem. 1973 Jun;354(6):613-27 PMID: 4803499
The interactions of proinsulin with insulin receptors on the plasma membrane of the liver.
J Clin Invest. 1974 Nov;54(5):1020-31 PMID: 4421396
Assay of insulin-like activity by the isolated fat cell method. I. Factors influencing the response to crystalline insulin.
Diabetologia. 1967 Aug;3(4):382-8 PMID: 5620795
[Preparation and properties of acetyl derivatives of beef insulin. I].
Hoppe Seylers Z Physiol Chem. 1972 Apr;353(4):599-617 PMID: 5053439
[Resynthesis of insulin from A-chains-monodisulfide-bis-S-sulfonate].
Hoppe Seylers Z Physiol Chem. 1968 Apr;349(4):385-9 PMID: 5652054
Insulin interactions with liver plasma membranes. Independence of binding of the hormone and its degradation.
J Biol Chem. 1972 Jun 25;247(12):3953-61 PMID: 5033396
Isolation of an organ specific protein antigen from cell-surface membrane of rat liver.
Biochim Biophys Acta. 1968 Apr 9;154(3):540-52 PMID: 4967807
Preparation of N A1 ,N B29 -adipoylinsulin, an intramolecularly crosslinked derivative of beef insulin.
Hoppe Seylers Z Physiol Chem. 1972 Jun;353(6):869-73 PMID: 5066108
Monoiodoinsulin: demonstration of its biological activity and binding to fat cells and liver membranes.
Biochem Biophys Res Commun. 1971 Apr 16;43(2):400-8 PMID: 5577450
Insulin receptors in the liver: specific binding of ( 125 I)insulin to the plasma membrane and its relation to insulin bioactivity.
Proc Natl Acad Sci U S A. 1971 Aug;68(8):1833-7 PMID: 4331561
Hypoglycemic activity and immunological half-life of porcine insulin and proinsulin in baboons and swine.
Endocrinology. 1971 Mar;88(3):714-7 PMID: 5541306
X-ray analysis and the structure of insulin.
Recent Prog Horm Res. 1971;27:1-40 PMID: 4946130
The biological activity and the binding affinity of modified insulins determined on isolated rat fat cells.
Diabetologia. 1974 Apr;10(2):105-13 PMID: 4367434

Article Info

Journal

Diabetologia

Abbr.

Diabetologia

ISSN

0012-186X

DOI

10.1007/BF00421406

Published

1974-02-00

Pages

1-5

Language

English

Region

Germany

NLM ID

0006777

Subset

External Links

PubMed source DOI: 10.1007/BF00421406 View journal details

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Receptor-binding assay of chemically modified insulins. Comparison with in vitro and in vivo bioassays.

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