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PMID: 4372170 Published · ppublish English Comparative Study Journal Article

Stimulation of peripheral blood lymphocytes by herpes simplex virus in vitro.

Infection and immunity ·Vol. 10 ·No. 3 ·1974-09-00 ·Pages 430-6

Scriba M

Abstract

A method for stimulating sensitized lymphocytes by inactivated herpes simplex virus was established by using cultures of washed whole blood cells. The development of the immune response of herpes simplex virus-infected guinea pigs was examined at different times in the 4-month period after infection. Humoral and cellular immune responses were compared in individual animals by measuring lymphocyte stimulation ratios and neutralizing serum antibodies.

MeSH Terms
Animals Antibodies, Viral/analysis Antibody Formation Antigens, Viral Blood Cells Blood Proteins/analysis Cells, Cultured DNA/biosynthesis Guinea Pigs Immunity Immunity, Cellular Immunization Lymphocyte Activation Lymphocytes/immunology Male Methods Neutralization Tests Simplexvirus/immunology Thymidine/metabolism Tritium Virus Replication
Chemicals
Antibodies, Viral Antigens, Viral Blood Proteins Tritium DNA Thymidine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Scriba M
References (37)
37 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.10.3.430-436.1974
Published
1974-09-00
Pages
430-6
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC422971
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.10.3.430-436.1974 PMC Full Text View journal details
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