Neutralizing activity in isolated serum antibody fractions from visna-infected sheep.

Infection and immunity ·Vol. 10 ·No. 3 ·1974-09-00 ·Pages 678-80

Mehta PD, Thormar H

Abstract

The neutralization technique was used to detect specific antibodies against visna virus in isolated immunoglobulin (Ig) G(1), IgG(2), and IgM fractions of visna-infected sheep serum. The neutralizing antibodies were present chiefly in the IgG(1) class. Low amount of activity was demonstrated in the IgM class, but no significant activity was seen in the IgG(2) class.

MeSH Terms

Animals Antibodies, Viral/analysis Complement Fixation Tests Hemagglutination Tests Immune Sera Immunoelectrophoresis Immunoglobulin G/analysis Immunoglobulin M/analysis Neutralization Tests RNA Viruses/immunology Rabbits/immunology Sheep Visna-maedi virus/immunology

Chemicals

Antibodies, Viral Immune Sera Immunoglobulin G Immunoglobulin M

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Mehta P D

Thormar H

References (10)

10 references, click to expand

A comparison of visna and maedi viruses. II. Serological relationship.
Res Vet Sci. 1965 Oct;6(4):456-65 PMID: 4955854
Characterization of the serum and secretory immune systems of the cow and sheep.
J Immunol. 1969 Aug;103(2):334-44 PMID: 5803790
Immunocytochemical localization of the ovine immunoglobulins IgA, IgG1, IgG1-A and IgG2: effect of gastro-intestinal parasitism in the sheep.
Clin Exp Immunol. 1971 Jan;8(1):151-62 PMID: 4924939
Experimental louping-ill in sheep and lambs. I. Viraemia and the antibody response.
J Comp Pathol. 1971 Apr;81(2):291-8 PMID: 5091668
The serum and secretory immunoglobulins of cattle: characterization and quantitation.
J Immunol. 1972 Apr;108(4):965-76 PMID: 4112418
Antibodies produced by rabbits immunized with visna virus.
Infect Immun. 1971 Dec;4(6):715-9 PMID: 4949510
Zone electrophoresis.
Methods Biochem Anal. 1954;1:141-70 PMID: 13193528
Visna, a demyelinating transmissible disease of sheep.
J Neuropathol Exp Neurol. 1957 Jul;16(3):389-403 PMID: 13439402
ISOLATION AND CHARACTERIZATION OF OVINE GAMMA GLOBULINS.
Arch Biochem Biophys. 1965 Jan;109:142-9 PMID: 14281939
[A micro-method of immuno-electrophoresis].
Int Arch Allergy Appl Immunol. 1955;7(2):103-10 PMID: 13262900

Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.10.3.678-680.1974

Published

1974-09-00

Pages

678-80

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC423005

Subset

External Links

PubMed source DOI: 10.1128/iai.10.3.678-680.1974 PMC Full Text View journal details

Analysis Services

Neutralizing activity in isolated serum antibody fractions from visna-infected sheep.

Contact

WeChat Official Account