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PMID: 4373726 Published · ppublish English Journal Article

Coexistence of several putative neurotransmitters in single identified neurons of Aplysia.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 71 ·No. 12 ·1974-12-00 ·Pages 4662-5

Brownstein MJ, Saavedra JM, Axelrod J, Zeman GH, Carpenter DO

Abstract

By sensitive enzymatic micromethods several putative neurotransmitters were measured in four identifiable neurons of Aplysia californica (R-2, R-14, L-11, and C-1). Serotonin was found in all of these neurons, and octopamine in all but C-1. Acetylcholine has been previously reported to be present in R-2 and L-11. The catecholamines, norepinephrine and dopamine, were not detected in the four cells examined. The possible biological consequence of the presence of several putative transmitters in single identifiable neurons is discussed.

MeSH Terms
Animals Dopamine/analysis Ganglia/cytology Histamine/analysis Mollusca/analysis Neurons/analysis Norepinephrine/analysis Octopamine/analysis Serotonin/analysis Synaptic Transmission
Chemicals
Octopamine Serotonin Histamine Dopamine Norepinephrine
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Brownstein M J
Saavedra J M
Axelrod J
Zeman G H
Carpenter D O
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26 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.71.12.4662
Published
1974-12-00
Pages
4662-5
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC433955
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.71.12.4662 PMC Full Text View journal details
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