Alpha-hydroxy acid oxidase: localization in renal microbodies.

Science (New York, N.Y.) ·Vol. 149 ·No. 3691 ·1965-09-24 ·Pages 1507-9

Allen JM, Beard ME

Abstract

Differential and density equilibrium centrifugation have established the presence of alpha-hydroxy acid oxidase in microbodies of the kidney of the rat. The enzyme has been demonstrated in cells of the distal convoluted tubule by a microscopic cytochemical method. This enzyme, like certain others in microbodies, produces hydrogen peroxide.

MeSH Terms

Acid Phosphatase/metabolism Alcohol Oxidoreductases/metabolism Animals D-Amino-Acid Oxidase/metabolism Electrophoresis Histocytochemistry In Vitro Techniques Keto Acids/pharmacology Kidney/enzymology Photometry Quinacrine/pharmacology Rats Succinate Dehydrogenase/metabolism

Chemicals

Keto Acids Alcohol Oxidoreductases Succinate Dehydrogenase D-Amino-Acid Oxidase Acid Phosphatase Quinacrine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Allen J M

Beard M E

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.149.3691.1507

Published

1965-09-24

Pages

1507-9

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.149.3691.1507 View journal details

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Alpha-hydroxy acid oxidase: localization in renal microbodies.

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