Inactivation of guanosine 5'-phosphate reductase by 6-chloro-, 6-mercapto-, and 2-amino-6-mercapto-9-beta-D-ribofuranosylpurine 5'-phosphates.

Adenosine Triphosphate Antineoplastic Agents/pharmacology Binding Sites Chemical Phenomena Chemistry Chlorine Enterobacter/enzymology Glutathione Guanine Nucleotides Iodoacetates Kinetics NADP Nucleosides Nucleotides Oxidoreductases/antagonists & inhibitors Sulfhydryl Compounds Thioguanine

Antineoplastic Agents Guanine Nucleotides Iodoacetates Nucleosides Nucleotides Sulfhydryl Compounds Chlorine NADP Adenosine Triphosphate Oxidoreductases Thioguanine Glutathione