Increased dihydrofolate reductase synthesis in Diplococcus pneumoniae following translatable alteration of the structural gene. 3. Further evidence on the extent of genic involvement.

Genetics ·Vol. 65 ·No. 3 ·1970-07-00 ·Pages 391-406

Sirotnak FM

Abstract

暂无摘要

MeSH Terms

Chromosome Mapping Crosses, Genetic Drug Stability Genes Methotrexate Mutation Operon Protein Binding Recombination, Genetic Streptococcus pneumoniae/enzymology Temperature Tetrahydrofolate Dehydrogenase/biosynthesis Transformation, Genetic

Chemicals

Tetrahydrofolate Dehydrogenase Methotrexate

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Sirotnak F M

References (16)

16 references, click to expand

GENETIC STUDIES ON AMETHOPTERIN RESISTANCE IN DIPLOCOCCUS PNEUMONIAE.
J Bacteriol. 1960 Nov;80(5):648-53 PMID: 16561877
Enzymatic characterization of 17 L-arabinose negative mutants of Escherichia coli.
J Bacteriol. 1961 Jun;81:996-1006 PMID: 13696894
Genetic recombination in DNA-induced transformation of Pneumococcus. II. Mapping the amiA region.
Genetics. 1965 Dec;52(6):1207-27 PMID: 4379828
Integration efficiency and genetic recombination in pneumococcal transformation.
Genetics. 1966 Jan;53(1):207-35 PMID: 4379022
Dual consequence of mutation in the dihydrofolate reductase gene of Diplococcus pneumoniae.
Biochem Biophys Res Commun. 1969 Aug 15;36(4):603-7 PMID: 4390189
COORDINATE VARIATIONS IN INDUCED SYNTHESES OF ENZYMES ASSOCIATED WITH MUTATIONS IN A STRUCTURAL GENE.
Proc Natl Acad Sci U S A. 1963 Oct;50:696-702 PMID: 14077500
A study of the genetic material determining an enzyme in Pneumococcus.
Biochim Biophys Acta. 1960 Apr 22;39:508-18 PMID: 14413322
Enzymatic reduction of dihydrofolic acid.
J Biol Chem. 1958 Oct;233(4):969-74 PMID: 13587525
Increased dihydrofolate reductase synthess in Diplococcus pneumoniae following translatable alteration of the structural gene. I. Genotype derivation and recombinational analyses.
Genetics. 1969 Feb;61(2):293-312 PMID: 4390084
Studies on the interaction of tritium-labeled aminopterin with dihydrofolic reductase.
Arch Biochem Biophys. 1963 Mar;100:525-30 PMID: 13992822
Increased dihydrofolate reductase synthesis in Diplococcus pneumoniae following translatable alteration of the structural gene. II. Individual and dual effects on the properties and rate of synthesis of the enzyme.
Genetics. 1969 Feb;61(2):313-26 PMID: 4390085
THE DISTRIBUTION OF MUTATIONAL SITES AFFECTING RESISTANCE TO AMETHOPTERIN IN DIPLOCOCCUS PNEUMONIAE.
Genetics. 1964 Mar;49:439-52 PMID: 14135405
FURTHER OBSERVATIONS OF THE BINDING AND INHIBITION OF DIHYDROFOLIC REDUCTASE BY FOLIC ACID ANTAGONISTS.
Biochem Pharmacol. 1964 May;13:731-42 PMID: 14181276
DIHYDROFOLATE REDUCTASE IN GENOTYPICALLY DISTINGUISHABLE AMETHOPTERIN-RESISTANT DIPLOCOCCUS PNEUMONIAE.
J Biol Chem. 1964 Aug;239:2677-82 PMID: 14235552
Protein measurement with the Folin phenol reagent.
J Biol Chem. 1951 Nov;193(1):265-75 PMID: 14907713
Dihydrofolate reductase from a resistant subline of the L1210 lymphoma. Purification and properties.
J Biol Chem. 1967 Oct 25;242(20):4771-6 PMID: 4964810

Article Info

Journal

Genetics

Abbr.

Genetics

ISSN

0016-6731

DOI

10.1093/genetics/65.3.391

Published

1970-07-00

Pages

391-406

Language

English

Region

United States

NLM ID

0374636

PMCID

PMC1212453

Subset

External Links

PubMed source DOI: 10.1093/genetics/65.3.391 PMC Full Text View journal details

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Increased dihydrofolate reductase synthesis in Diplococcus pneumoniae following translatable alteration of the structural gene. 3. Further evidence on the extent of genic involvement.

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