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PMID: 441739 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Periodicity of deoxyribonuclease I digestion of chromatin.

Science (New York, N.Y.) ·Vol. 204 ·No. 4395 ·1979-05-25 ·Pages 855-8

Prunell A, Kornberg RD, Lutter L, Klug A, Levitt M, Crick FH

Abstract

Two methods have been used to measure the single-strand lengths of the DNA fragments produced by deoxyribonuclease I digestion of chromatin. The average lengths obtained are muliples of about 10.4 bases, significantly different from the value of 10 previously reported. This periodicity in fragment lengths is closely related to the periodicity of the DNA double helix in chromatin, but the two values need not be exactly the same.

MeSH Terms
Animals Base Sequence Chromatin/metabolism,ultrastructure Deoxyribonucleases/metabolism Hydrolysis Molecular Weight Rats
Chemicals
Chromatin Deoxyribonucleases
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Prunell A
Kornberg R D
Lutter L
Klug A
Levitt M
Crick F H
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1979-05-25
Pages
855-8
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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