Evidence for the direct binding of polyamines to a ribonuclease that hydrolyzes ribonucleic acid at uridylic acid residues.

Amino Acids/analysis Binding Sites Carbon Radioisotopes Cations, Divalent Chromatography, Gel Chromatography, Ion Exchange Citrobacter/enzymology Escherichia/enzymology Guanine Nucleotides Kinetics Macromolecular Substances Polynucleotides/pharmacology Protein Binding Putrescine Ribonucleases/metabolism Spectrophotometry, Ultraviolet Spermidine Spermine Structure-Activity Relationship Tritium Trypsin Uracil Nucleotides

Amino Acids Carbon Radioisotopes Cations, Divalent Guanine Nucleotides Macromolecular Substances Polynucleotides Uracil Nucleotides Tritium Spermine Ribonucleases Trypsin Spermidine Putrescine