Serological detection of a cell-surface antigen specified by the T (brachyury) mutant gene in the house mouse.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 69 ·No. 8 ·1972-08-00 ·Pages 2076-80

Bennett D, Goldberg E, Dunn LC, Boyse EA

Abstract

A cell-surface component specified by a mutant gene at the T-locus in the mouse has been detected on sperm by serological methods. The gene product thus recognized is not present on other adult cells.

MeSH Terms

Animals Antibody Specificity Antigen-Antibody Reactions Antigens/analysis Brain/immunology Cell Membrane/immunology Cytotoxicity Tests, Immunologic Genes, Lethal Lymphocytes/immunology Male Mice Mice, Inbred Strains Mutation Spermatozoa/immunology Tail/abnormalities Testis/immunology Thymus Gland/immunology

Chemicals

Antigens

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Bennett D

Goldberg E

Dunn L C

Boyse E A

References (9)

9 references, click to expand

On the structure of the XY bivalent in Mus musculus L.
Chromosoma. 1963;13:521-5 PMID: 13947455
Cytological identification of the chromosome carrying the IXth linkage group (including H-2) in the house mouse.
Proc Natl Acad Sci U S A. 1971 Jul;68(7):1594-7 PMID: 5283950
Studies of the Genetic Variability in Wild Populations of House Mice. I. Analysis of Seven Alleles at Locus T.
Genetics. 1956 May;41(3):344-52 PMID: 17247632
ABNORMALITIES ASSOCIATED WITH A CHROMOSOME REGION IN THE MOUSE. I. TRANSMISSION AND POPULATION GENETICS OF THE T-REGION.
Science. 1964 Apr 17;144(3616):260-3 PMID: 14169709
Detection of H-2 antigens on mouse spermatozoa by the cytotoxicity test.
Nature. 1970 Nov 7;228(5271):570-2 PMID: 5528693
Synthetic activities during spermatogenesis in the mouse RNA and protein.
Exp Cell Res. 1965 Aug;39(1):197-224 PMID: 5318974
BENNETT D, BEASLEY AB: Mutation and recombination in the vicinity of a complex gene.
Genetics. 1962 Mar;47:285-303 PMID: 13888509
Serologically demonstrable alloantigens of mouse epidermal cells.
J Exp Med. 1972 Apr 1;135(4):938-55 PMID: 4553016
The genetics of the mammalian gamete.
Biol Rev Camb Philos Soc. 1970 Feb;45(1):73-119 PMID: 5310031

Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.69.8.2076

Published

1972-08-00

Pages

2076-80

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC426872

Subset

External Links

PubMed source DOI: 10.1073/pnas.69.8.2076 PMC Full Text View journal details

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Serological detection of a cell-surface antigen specified by the T (brachyury) mutant gene in the house mouse.

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