The prevention by inhibitors of brain proptein synthesis of the hyperactivity and hyperpyrexia produced in rats by monoamine oxidase inhibition and the administration of L-tryptophan or 5-methoxy-N,N-dimethyltryptamine.

Amphetamine/pharmacology Animals Brain/metabolism Carbon Isotopes Cycloheximide/pharmacology Emetine/pharmacology Fever/chemically induced,prevention & control Hallucinogens/pharmacology Humans Hyperkinesis/chemically induced,prevention & control Male Methyl Ethers/pharmacology N,N-Dimethyltryptamine/pharmacology Nerve Tissue Proteins/biosynthesis Puromycin/pharmacology Rats Serotonin/biosynthesis,metabolism Time Factors Tranylcypromine/pharmacology Tryptophan/pharmacology

Carbon Isotopes Hallucinogens Methyl Ethers Nerve Tissue Proteins Serotonin Tranylcypromine Puromycin Tryptophan Cycloheximide Amphetamine N,N-Dimethyltryptamine Emetine