Separation of serum bactericidal and opsonizing activities for Haemophilus influenzae type b.

Infection and immunity ·Vol. 8 ·No. 3 ·1973-09-00 ·Pages 488-90

Newman SL, Waldo B, Johnston RB

Abstract

When assay conditions permitted bacterial growth, immune serum had no bactericidal activity for Haemophilus influenzae but promoted rapid phagocytic killing of this organism by human leukocytes.

MeSH Terms

Blood Bactericidal Activity Haemophilus influenzae/immunology Hemagglutination Tests Humans Immune Sera Opsonin Proteins Phagocytosis Ultrasonics

Chemicals

Immune Sera Opsonin Proteins

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Newman S L

Waldo B

Johnston R B

References (8)

8 references, click to expand

In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood.
J Clin Invest. 1967 Apr;46(4):668-79 PMID: 6021213
Studies of polymorphonuclear leukocytes from patients with chronic granulomatous disease of childhood: bactericidal capacity for streptococci.
Pediatrics. 1968 Mar;41(3):591-9 PMID: 4966707
The enhancement of bacterial phagocytosis by serum. The role of complement components and two cofactors.
J Exp Med. 1969 Jun 1;129(6):1275-90 PMID: 4181833
Metabolic and bactericidal activities of human eosinophils.
Br J Haematol. 1971 Mar;20(3):277-85 PMID: 5552359
Chronic granulomatous disease: correlation between pathogenesis and clinical findings.
Pediatrics. 1971 Nov;48(5):730-9 PMID: 5121235
Human serum activities against Hemophilus influenzae, type b.
J Clin Invest. 1972 Jan;51(1):31-8 PMID: 4536614
Immunization of humans with polyribophosphate, the capsular antigen of Hemophilus influenzae, type b.
J Clin Invest. 1972 Jan;51(1):39-44 PMID: 4536615
Characterization of human antibody to polyribophosphate, the capsular antigen of Hemophilus influenzae, type B.
Clin Immunol Immunopathol. 1973 Jan;1(2):234-40 PMID: 4543490

Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.8.3.488-490.1973

Published

1973-09-00

Pages

488-90

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC422876

Subset

External Links

PubMed source DOI: 10.1128/iai.8.3.488-490.1973 PMC Full Text View journal details

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Separation of serum bactericidal and opsonizing activities for Haemophilus influenzae type b.

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