Antigen-initiated B lymphocyte differentiation. Characterisation of the primary and secondary immune responses of normal and athymic mice to the hapten 4-hydroxy-3-iodo-5-nitrophenylacetic acid presented on the carrier polymerised bacterial flagellin.

Animals Antibody Formation Antibody-Producing Cells/metabolism Antigens, Bacterial B-Lymphocytes/metabolism Female Flagella/immunology Haptens Immunoglobulin G/biosynthesis Immunoglobulin M/biosynthesis Immunologic Deficiency Syndromes/immunology Immunologic Memory Kinetics Male Mice Nitro Compounds Phenylacetates Salmonella/immunology T-Lymphocytes/immunology,metabolism Thymus Gland/abnormalities Time Factors

Antigens, Bacterial Haptens Immunoglobulin G Immunoglobulin M Nitro Compounds Phenylacetates