The pi-histidine factor of Salmonella typhimurium: a demonstration that pi-histidine factor integrates into the chromosome.

Journal of bacteriology ·Vol. 109 ·No. 3 ·1972-03-00 ·Pages 993-1000

Levinthal M, Yeh J

Abstract

The Salmonella typhimurium pi-histidine episome was identified by Ames et al. (2) in an unstable partial revertant of a deletion mutation-containing strain, hisG203. HisG203 lacks the histidine operator, promoter, and part of the first structural gene. In this paper, we study some properties of pi factor and demonstrate a low frequency of pi integration into the chromosome at or near the histidine region.

MeSH Terms

Acridines/pharmacology Alcohol Oxidoreductases/metabolism Amino Alcohols Chromosome Mapping Chromosomes, Bacterial/metabolism Conjugation, Genetic Culture Media Diploidy Genes Histidine/metabolism Hydro-Lyases/metabolism Ligases/metabolism Mutagens Mutation Nitrosoguanidines Operon Penicillins Phosphogluconate Dehydrogenase/metabolism Recombination, Genetic Ribonucleotides Salmonella typhimurium/drug effects,enzymology,growth & development,metabolism Transduction, Genetic

Chemicals

Acridines Amino Alcohols Culture Media Mutagens Nitrosoguanidines Penicillins Ribonucleotides Histidine Alcohol Oxidoreductases Phosphogluconate Dehydrogenase Hydro-Lyases Ligases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Levinthal M

Yeh J

References (15)

15 references, click to expand

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Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.109.3.993-1000.1972

Published

1972-03-00

Pages

993-1000

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC247319

Subset

External Links

PubMed source DOI: 10.1128/jb.109.3.993-1000.1972 PMC Full Text View journal details

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The pi-histidine factor of Salmonella typhimurium: a demonstration that pi-histidine factor integrates into the chromosome.

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