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PMID: 4553679 Published · ppublish English Journal Article

Comparisons of the distribution of nucleotides and common sequences in deoxyribonucleic acid from selected bacteriophages.

Journal of virology ·Vol. 9 ·No. 4 ·1972-04-00 ·Pages 583-93

Skalka SA, Hanson P

Abstract

Results from comparisons of deoxyribonucleic acid (DNA) from several classes of bacteriophages suggest that most phage chromosomes contain either a homogeneous distribution of nucleotides or are made up of a few, rather large segments of different quanine plus cytosine (G + C) contents which are internally homogeneous. Among those temperate phages tested, most contained segmented DNA. Comparisons of sequence similarities among segments from lambdoid phage DNA species revealed the following order in relatedness to lambda: 82 (and 434) > 21 > 424 > phi80. Most common sequences are found in the highest G + C segments, which in lambda contain head and tail genes. Hybridization tests with lambda and 186 or P2 DNA species verified that the lambdoids and 186 and P2 belong to two distinct groups. There are fewer homologous sequences between the DNA species of coliphages lambda and P2 or 186 than there are between the DNA species of coliphage lambda and salmonella phage P22.

MeSH Terms
Base Sequence Centrifugation, Density Gradient Cesium Chromosome Mapping Coliphages/analysis Cytosine/analysis DNA, Viral/analysis Escherichia coli Guanine/analysis Lysogeny Mercury Molecular Weight Nucleic Acid Hybridization Nucleotides/analysis Phosphorus Isotopes Salmonella Phages/analysis Salmonella typhimurium Sulfates Thymidine Tritium
Chemicals
DNA, Viral Nucleotides Phosphorus Isotopes Sulfates Tritium Cesium Guanine Cytosine Mercury Thymidine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Skalka S A
Hanson P
References (51)
51 references, click to expand
  1. Infectivity of phage P2 DNA in presence of helper phage.
    Mol Gen Genet. 1967;99(1):88-96 PMID: 4869987
  2. Genetic studies on bacteriophage P1.
    Virology. 1968 Dec;36(4):564-74 PMID: 4881411
  3. A membrane-filter technique for the detection of complementary DNA.
    Biochem Biophys Res Commun. 1966 Jun 13;23(5):641-6 PMID: 5963888
  4. THE STRUCTURAL GENE FOR lambda EXONUCLEASE.
    Proc Natl Acad Sci U S A. 1967 Feb;57(2):277-83 PMID: 16591465
  5. Nucleotide distribution and functional orientation in the deoxyribonucleic acid of phage phi 80.
    J Virol. 1969 Feb;3(2):150-6 PMID: 5774137
  6. Replication of phage lambda DNA.
    Cold Spring Harb Symp Quant Biol. 1968;33:533-51 PMID: 4891991
  7. Regulation of in vitro translation of bacteriophage f2 RNA.
    Cold Spring Harb Symp Quant Biol. 1969;34:655-73 PMID: 4909522
  8. Gene order in prophage P22.
    Virology. 1965 Oct;27(2):229-31 PMID: 5840894
  9. A phage P22 gene controlling integration of prophage.
    Virology. 1967 Feb;31(2):207-16 PMID: 6021093
  10. Sedimentation rate as a measure of molecular weight of DNA.
    Biophys J. 1963 Jul;3:309-21 PMID: 14016998
  11. Secondary structure of DNA depends on base composition.
    Nat New Biol. 1971 Aug 11;232(2):174-6 PMID: 4328209
  12. The process of infection with coliphage T7. IV. Stability of RNA in bacteriophage-infected cells.
    J Mol Biol. 1970 Aug;51(3):671-8 PMID: 4099510
  13. DNA replication and messenger RNA production after induction of wild-type lambda bacteriophage and lambda mutants.
    J Mol Biol. 1966 Aug;19(1):174-86 PMID: 5967282
  14. The rule of the ring.
    J Cell Physiol. 1967 Oct;70(2):Suppl:13-33 PMID: 4867582
  15. Clear plaque mutants of phage P1.
    Virology. 1970 May;41(1):66-71 PMID: 5444276
  16. Genetic control of transcription during development of phage gamma.
    Proc Natl Acad Sci U S A. 1967 Aug;58(2):576-83 PMID: 4860753
  17. Changes in molecular weight of DNA accompanying mutations in phage.
    Proc Natl Acad Sci U S A. 1963 Feb 15;49:151-5 PMID: 14016999
  18. A defective P1 prophage with a chromosomal location.
    Virology. 1970 Jan;40(1):144-51 PMID: 4903858
  19. Polypeptide chain initiation: nucleotide sequences of the three ribosomal binding sites in bacteriophage R17 RNA.
    Nature. 1969 Dec 6;224(5223):957-64 PMID: 5360547
  20. Distribution of nucleotides in Escherichia coli DNA from lambda-transducing phages.
    J Mol Biol. 1971 Jun 14;58(2):417-30 PMID: 4933411
  21. Melting temperatures of the cohesive ends of some non-inducible coliphage DNA's.
    J Mol Biol. 1968 Nov 28;38(1):137-9 PMID: 5760631
  22. The circularity of the phage P22 linkage map.
    Genetics. 1968 Feb;58(2):161-9 PMID: 5664382
  23. Transducing fragments in generalized transduction by phage P1. I. Molecular origin of the fragments.
    J Mol Biol. 1965 Nov;14(1):85-109 PMID: 5883923
  24. Localization of P2 prophage in two strains of Escherichia coli.
    Virology. 1963 Jan;19:32-9 PMID: 14042138
  25. Non-Darwinian evolution.
    Science. 1969 May 16;164(3881):788-98 PMID: 5767777
  26. Conformational changes of single-stranded DNA.
    J Mol Biol. 1969 Apr;41(2):189-97 PMID: 5801473
  27. Prophage P1, and extrachromosomal replication unit.
    Cold Spring Harb Symp Quant Biol. 1968;33:791-8 PMID: 4892009
  28. Position of branch points in replicating lambda DNA.
    J Mol Biol. 1970 Jul 14;51(1):61-73 PMID: 5481280
  29. The molecular origin of lambda prophage mRNA.
    Proc Natl Acad Sci U S A. 1969 Feb;62(2):385-8 PMID: 4894327
  30. Rapid bacteriophage sedimentation in the presence of polyethylene glycol and its application to large-scale virus purification.
    Virology. 1970 Mar;40(3):734-44 PMID: 4908735
  31. Segmental distribution of nucleotides in the DNA of bacteriophage lambda.
    J Mol Biol. 1968 May 28;34(1):1-16 PMID: 4999721
  32. Cohesive sites and helper phage function of P2, lambda, and 186 DNA's.
    Proc Natl Acad Sci U S A. 1968 May;60(1):265-8 PMID: 5241529
  33. The P22 bacteriophage DNA molecule. I. The mature form.
    J Mol Biol. 1968 Oct 14;37(1):21-40 PMID: 4939038
  34. Physical properties of phage 299.
    Mol Gen Genet. 1970;180(2):158-66 PMID: 5475575
  35. Noncomplementarity in base sequences between the cohesive ends of coliphages 186 and lambda and the formation of interlocked rings between the two DNA's.
    Biopolymers. 1967;5(10):953-66 PMID: 6078882
  36. Thermal chromatography of DNA-DNA reactions.
    Biophys J. 1967 Sep;7(5):567-84 PMID: 4860487
  37. Multiple units of transcription in phage lambda.
    Cold Spring Harb Symp Quant Biol. 1966;31:377-9 PMID: 5237196
  38. Cohesive sites on the deoxyribonucleic acids from several temperate coliphages.
    J Mol Biol. 1966 Jun;17(2):343-57 PMID: 5336321
  39. New RNA polymerase from Escherichia coli infected with bacteriophage T7.
    Nature. 1970 Oct 17;228(5268):227-31 PMID: 4920917
  40. Effects of the conformation of single-stranded DNA on renaturation and aggregation.
    J Mol Biol. 1969 Apr;41(2):199-209 PMID: 5801474
  41. Action of the lambda chromosome. I. Control of functions late in bacteriophage development.
    J Mol Biol. 1966 Aug;19(1):187-201 PMID: 5967283
  42. Starting point and direction of replication in P2 DNA.
    J Mol Biol. 1971 Jan 14;55(1):31-8 PMID: 4926974
  43. Regional and temporal control of genetic transcription in phage lambda.
    Proc Natl Acad Sci U S A. 1966 May;55(5):1190-5 PMID: 5225516
  44. Cohesion occurring between DNA molecules of temperate phages phi 80 and lambda or phi 81.
    Biochem Biophys Res Commun. 1965 Sep 22;20(6):727-32 PMID: 5861691
  45. Heat denaturation of P2 bacteriophage DNA: compositional heterogeneity.
    J Mol Biol. 1969 Sep 28;44(3):533-49 PMID: 4899476
  46. An amber map of Salmonella phage P22.
    Mol Gen Genet. 1969 Aug 15;104(4):339-50 PMID: 5367410
  47. The genetics and physiology of bacteriophage T7.
    Virology. 1969 Nov;39(3):562-74 PMID: 4902069
  48. Molecular weights of coliphages and coliphage DNA. IV. Molecular weights of DNA from bacteriophages T4, T5 and T7 and the general problem of determination of M.
    J Mol Biol. 1970 Dec 28;54(3):567-77 PMID: 4923669
  49. Cyclization of coliphage 186 DNA.
    J Mol Biol. 1967 Sep 28;28(3):403-11 PMID: 6052645
  50. Defective phage formation by lysogens of integration deficient phage P22 mutants.
    Virology. 1968 Feb;34(2):203-23 PMID: 4867906
  51. Preparation and characterization of temperate, non-inducible bacteriophage P2 (host: Escherichia coli).
    J Gen Virol. 1970 Feb;6(2):201-12 PMID: 4908574
Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.9.4.583-593.1972
Published
1972-04-00
Pages
583-93
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC356342
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.9.4.583-593.1972 PMC Full Text View journal details
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