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PMID: 456273 Published · ppublish ger English Abstract Journal Article

[A new concept in the surgery of chronic pancreatitis (author's transl)].

Ein neues Konzept in der Chirurgie der chronischen Pankreatitis.

Deutsche medizinische Wochenschrift (1946) ·Vol. 104 ·No. 28 ·1979-07-13 ·Pages 1003-6

Gall FP, Gebhardt C

Abstract

There is an obvious advantage to partial duodenopancreatectomy with occlusion of the pancreatic duct by prolamine (a rapidly solidifying aminoacid solution) for the prevention of recurrences, while preserving the stomach and proximal duodenum, in the treatment of severe destruction of the pancreas, localised to the head or generalised. The death rate of partial duodenopancreactectomy has been lowered from 8.5 to 2.3% since using this method. Compared with total duodenopancreatectomy which--according to the authors' earlier results carried a postoperative mortality of 20%--the operative risk has been reduced to a tenth. Taking into account the benign nature of chronic pancreatitis, on the other hand, and the extent of the operative operation, on the other, the present death-rate of 2.3% would appear reasonable. Occlusion of the pancreatic duct with prolamine in order to exclude any still present excretory pancreatic function in the residual pancreatic tissue has made all patients pain-free. No early recurrence has been observed.

MeSH Terms
Amino Acids/pharmacology Chronic Disease Humans Pancreatectomy/methods Pancreatic Ducts/drug effects Pancreatitis/surgery Proteins/pharmacology
Chemicals
Amino Acids Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Gall F P
Gebhardt C
Article Info
Journal
Deutsche medizinische Wochenschrift (1946)
Abbr.
Dtsch Med Wochenschr
ISSN
0012-0472
Published
1979-07-13
Pages
1003-6
Language
ger
Region
Germany
NLM ID
0006723
Subset
IM
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