Evidence for an extrakaryotic mutation affecting the maintenance of the rho factor in yeast.
A newly isolated, temperature-sensitive mutant of a haploid strain of Saccharomyces cerevisiae is described. Its shift to nonpermissive temperature (35 C) resulted in an irreversible change to rho(-), causing, within four to six generations, more than 90% of the cells to form petite colonies. Genetic analysis revealed extrakaryotic inheritance of this temperature-sensitive mutation. Data presented indicate mutation of a gene in the mitochondrial deoxyribonucleic acid affecting the maintenance of the rho factor.
13 references, click to expand
-
Quantitative selection of respiratory deficient mutants in yeasts by triphenyltetrazolium chloride.Z Naturforsch B. 1972 Mar;27(3):252-6 PMID: 4402625
-
Biogenesis of mitochondria. XXI. Studies on the nature of the mitochondrial genome in yeast: the degenerative effects of ethidium bromide on mitochondrial genetic information in a respiratory competent strain.J Mol Biol. 1972 Apr 28;66(1):181-93 PMID: 4557196
-
Inhibition of respiratory enzyme synthesis in yeast by chloramphenicol: relationship between chloramphenicol tolerance and resistance to other antibacterial antibiotics.Genet Res. 1967 Oct;10(2):199-203 PMID: 6064107
-
Protein synthesis by yeast promitochondria in vivo.Biochem Biophys Res Commun. 1969 Dec 4;37(6):996-1001 PMID: 5361166
-
Inhibition of mitochondrial protein synthesis in vivo by erythromycin in Schizosaccharomyces pombe and Saccharomyces cerevisiae.Mol Gen Genet. 1971;111(3):235-41 PMID: 4998252
-
Induction of the cytoplasmic petite mutation in Saccharomyces cerevisiae by the antibacterial antibiotics erythromycin and chloramphenicol.Mol Gen Genet. 1971;111(3):209-23 PMID: 5563934
-
Mitochondrial DNA and suppressiveness of petite mutants in Saccharomyces cerevisiae.Biochem Genet. 1971 Oct;5(5):487-95 PMID: 5520795
-
Hybridization of mitochondrial transfer RNA's with mitochondrial and nuclear DNA of grande (wild type) yeast.J Mol Biol. 1972 Feb 14;63(3):431-40 PMID: 4552406
-
Extrachromosomal inheritance of oligomycin resistance in yeast.FEBS Lett. 1970 Feb 25;6(4):302-304 PMID: 11947400
-
Low temperature and chloramphenicol induction of respiratory deficiency in a cold-sensitive mutant of Saccharomyces cerevisiae.Proc Natl Acad Sci U S A. 1970 Sep;67(1):52-8 PMID: 5272328
-
Mitochondrial genetics. I. Methodology and phenomenology.Symp Soc Exp Biol. 1970;24:449-96 PMID: 5516343
-
Biocide resistance in yeast: Isolation and general properties of trialkyl tin resistant mutants.FEBS Lett. 1971 Oct 1;17(2):209-214 PMID: 11946031
-
Mitochondrial DNA deficient petite mutants of yeast.Biochem Biophys Res Commun. 1970 Jun 5;39(5):989-96 PMID: 5423835
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