Amber mutant of bacteriophage Q capable of causing overproduction of Q replicase.

Journal of virology ·Vol. 11 ·No. 4 ·1973-04-00 ·Pages 603-5

Palmenberg A, Kaesberg P

Abstract

Amber mutant amB86 of bacteriophage Qbeta is capable of causing the production of five to eight times more viral replicase than wild-type phage. Su(-) bacteria infected with the mutant can carry the viral RNA in a plasmid-like state for many bacterial generations.

MeSH Terms

Cell-Free System Coliphages/enzymology,growth & development DNA-Directed RNA Polymerases/biosynthesis,metabolism Escherichia coli/growth & development Extrachromosomal Inheritance Genes Mutation Protein Biosynthesis RNA Viruses/enzymology,growth & development Tritium Uracil Nucleotides/metabolism Viral Proteins/biosynthesis

Chemicals

Uracil Nucleotides Viral Proteins Tritium DNA-Directed RNA Polymerases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Palmenberg A

Kaesberg P

References (4)

4 references, click to expand

Azure mutants: a type of host-dependent mutant of the bacteriophage f2.
Science. 1967 Jun 23;156(3782):1618-23 PMID: 6025122
Three cistrons in bacteriophage Q beta.
Virology. 1970 Sep;42(1):49-60 PMID: 4918276
Characterization of the initial peptide of Q-beta RNA polymerase and control of its synthesis.
Proc Natl Acad Sci U S A. 1971 Feb;68(2):276-9 PMID: 5277068
A new method for the purification of Q RNA-dependent RNA polymerase.
Biochim Biophys Acta. 1972 Feb 23;262(1):88-100 PMID: 4552904

Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.11.4.603-605.1973

Published

1973-04-00

Pages

603-5

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC355144

Subset

External Links

PubMed source DOI: 10.1128/JVI.11.4.603-605.1973 PMC Full Text View journal details

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Amber mutant of bacteriophage Q capable of causing overproduction of Q replicase.

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