Immunity to syphilis. I. Passive transfer in rabbits with hyperimmune serum.

Infection and immunity ·Vol. 8 ·No. 5 ·1973-11-00 ·Pages 787-90

Perine PL, Weiser RS, Klebanoff SJ

Abstract

Passive transfer of humoral immunity to experimental syphilis in rabbits was accomplished with large doses of hyperimmune serum. When the serum was administered before inoculation of Treponema pallidum, the onset of chancres was delayed; when it was given early in the course of infection, a transient period of arrest and healing of the chancres was imposed.

MeSH Terms

Animals Antibodies, Bacterial/analysis Immune Sera Immunity, Maternally-Acquired Immunization, Passive Male Rabbits/immunology Skin/pathology Syphilis/immunology,pathology Treponema Immobilization Test Treponema pallidum/immunology

Chemicals

Antibodies, Bacterial Immune Sera

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Perine P L

Weiser R S

Klebanoff S J

References (4)

4 references, click to expand

Lymphokine toxicity for yeast cells.
J Immunol. 1973 May;110(5):1444-6 PMID: 4572637
Influence of lysozyme upon the treponeme immobilization reaction.
Am J Hyg. 1961 Mar;73:236-44 PMID: 13769911
Production of immobilizing antibodies unaccompanied by active immunity to Treponema pallidum as shown by injecting rabbits and mice with the killed organisms.
Am J Syph Gonorrhea Vener Dis. 1953 Jan;37(1):9-22 PMID: 13016902
The production of Herxheimer reactions by injection of immune serum in rabbits with experimental syphilis.
Am J Syph Gonorrhea Vener Dis. 1951 Sep;35(5):405-10 PMID: 14878087

Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.8.5.787-790.1973

Published

1973-11-00

Pages

787-90

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC422928

Subset

External Links

PubMed source DOI: 10.1128/iai.8.5.787-790.1973 PMC Full Text View journal details

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Immunity to syphilis. I. Passive transfer in rabbits with hyperimmune serum.

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