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PMID: 4587384 Published · ppublish English Journal Article

Studies on toxinogenesis in Vibrio cholerae. II. An vitro test for enterotoxin production.

Infection and immunity ·Vol. 9 ·No. 1 ·1974-01-00 ·Pages 195-7

Vasil ML, Holmes RK, Finkelstein RA

Abstract

An Elek test for enterotoxin-producing strains of Vibrio cholerae is described. Thirty-five out of 37 strains of classical V. cholerae produced positive reactions, but only 1 of 69 E1 Tor vibrio strains was reactive. Tox(-) mutants of V. cholerae were also unreactive in the Elek test.

MeSH Terms
Animals Antigens, Bacterial Antitoxins Bacteriological Techniques Enterotoxins/analysis,biosynthesis Horses/immunology Immune Sera Precipitin Tests Vibrio cholerae/classification,immunology,metabolism
Chemicals
Antigens, Bacterial Antitoxins Enterotoxins Immune Sera
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Vasil M L
Holmes R K
Finkelstein R A
References (6)
6 references, click to expand
  1. The recognition of toxicogenic bacterial strains in vitro.
    Br Med J. 1948 Mar 13;1(4549):493-6 PMID: 18904096
  2. Pathogenesis of experimental cholera: biologic ativities of purified procholeragen A.
    J Immunol. 1966 Mar;96(3):440-9 PMID: 4956587
  3. The in vitro test for virulence of Corynebacterium diphtheriae.
    Am J Public Health Nations Health. 1949 Oct;39(10):1314-20 PMID: 18141126
  4. Monospecific equine antiserum against cholera exo-enterotoxin.
    Infect Immun. 1970 Dec;2(6):691-7 PMID: 16557901
  5. Pathogenesis of experimental cholera: identification of choleragen (procholeragen A) by disc immunoelectrophoresis and its differentiation from cholera mucinase.
    J Immunol. 1966 Jul;97(1):25-33 PMID: 5920457
  6. Antitoxic immunity in experimental cholera: observations with purified antigens and the ligated ileal loop model.
    Infect Immun. 1970 May;1(5):464-7 PMID: 16557759
Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.9.1.195-197.1974
Published
1974-01-00
Pages
195-7
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC414785
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.9.1.195-197.1974 PMC Full Text View journal details
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