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PMID: 4594033 Published · ppublish English Journal Article

Size and structure of yeast chromosomal DNA.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 70 ·No. 11 ·1973-11-00 ·Pages 3072-6

Petes TD, Byers B, Fangman WL

Abstract

Electron microscopic analysis indicates that yeast nuclear DNA can be isolated as linear molecules ranging in size from 50 mum (1.2 x 10(8) daltons) to 355 mum (8.4 x 10(8) daltons). Analysis indicates the data is consistent with the hypothesis that each yeast chromosome contains a single, linear DNA duplex. Mitochondrial DNA molecules have a contour length of 21 +/- 2 mum and are mostly linear.

MeSH Terms
Carbon Radioisotopes Centrifugation, Density Gradient Chromosomes/analysis Coliphages/analysis DNA/isolation & purification DNA, Mitochondrial/analysis DNA, Viral Microscopy, Electron Molecular Weight Nucleic Acid Conformation Saccharomyces cerevisiae/analysis Tritium
Chemicals
Carbon Radioisotopes DNA, Mitochondrial DNA, Viral Tritium DNA
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Petes T D
Byers B
Fangman W L
References (20)
20 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.70.11.3072
Published
1973-11-00
Pages
3072-6
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC427172
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.70.11.3072 PMC Full Text View journal details
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