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PMID: 4598218 Published · ppublish English Journal Article

Drug-resistant Escherichia coli and Klebsiella-Enterobacter in healthy adults in Thailand and the effect of antibiotic administration.

Antimicrobial agents and chemotherapy ·Vol. 4 ·No. 2 ·1973-08-00 ·Pages 198-200

Koonkhamlert C, Sawyer WD

Abstract

Antibiotic-resistant strains of Escherichia coli and, to a lesser extent, Klebsiella-Enterobacter were common in serial samples of the normal intestinal flora of healthy young adults in Thailand, and the resistance often was to multiple drugs and was transferable. Antibiotic administration promoted dominance of the flora by drug-resistant organisms regardless of the drug regimen and the predrug susceptibility pattern of the flora. The normal pattern was regained slowly after the cessation of drug administration.

MeSH Terms
Adult Anti-Bacterial Agents/pharmacology Drug Resistance, Microbial Escherichia coli/drug effects Humans Intestines/microbiology Klebsiella/drug effects Thailand
Chemicals
Anti-Bacterial Agents
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Koonkhamlert C
Sawyer W D
References (16)
16 references, click to expand
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
Published
1973-08-00
Pages
198-200
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC444528
Subset
IM
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