Target of inhibition by the anti-lipogenic antibiotic cerulenin of sterol synthesis in yeast.

Acetoacetates Acetyl Coenzyme A/metabolism Acetyltransferases/metabolism Antifungal Agents/pharmacology Carbon Radioisotopes Cell-Free System Coenzyme A Ethers, Cyclic/pharmacology Fatty Acids, Unsaturated/pharmacology Glutarates Mevalonic Acid/metabolism Oxo-Acid-Lyases/antagonists & inhibitors Phytosterols/biosynthesis Saccharomyces cerevisiae/drug effects,enzymology Spectrophotometry, Ultraviolet Time Factors

Acetoacetates Antifungal Agents Carbon Radioisotopes Ethers, Cyclic Fatty Acids, Unsaturated Glutarates Phytosterols Acetyl Coenzyme A Acetyltransferases Oxo-Acid-Lyases Mevalonic Acid Coenzyme A