Mycolic acids from "noncultivable" mycobacteria.

Infection and immunity ·Vol. 10 ·No. 1 ·1974-07-00 ·Pages 236-9

Etemadi AH, Convit J

Abstract

Chromatographic analysis, coupled to mass spectrometry with a high-resolution mass spectrometer, of materials isolated from skin lesions of patients with lepromatous leprosy allows the recognition of characteristic mycobacterial products, mycolic acids. This finding indicates that the "noncultivable" bacteria responsible for leprosy are mycobacteria.

MeSH Terms

Acetone Chromatography, Thin Layer Ethanol Ethers Humans Leprosy/metabolism,microbiology Mass Spectrometry Mycobacterium/isolation & purification Mycobacterium leprae/metabolism Mycolic Acids/analysis Skin Manifestations

Chemicals

Ethers Mycolic Acids Acetone Ethanol

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Etemadi A H

Convit J

References (5)

5 references, click to expand

Cytochemical reactions of human leprosy bacilli and mycobacteria: ultrastructural implications.
J Bacteriol. 1973 Mar;113(3):1389-99 PMID: 4120605
Elimination of the acid fastness but not the gram positivity of leprosy bacilli after extraction with pyridine.
J Bacteriol. 1971 May;106(2):707-8 PMID: 4102336
Identification of the noncultivable pathogenic mycobacteria M. leprae and M. lepraemurium.
Int J Lepr Other Mycobact Dis. 1968 Apr-Jun;36(2):166-70 PMID: 4877114
[Mycolic acids. Structure, biogenesis and phylogenetic value].
Expos Annu Biochim Med. 1967;28:77-109 PMID: 4883169
[Structural and biogenetic correlations of mycolic acids in relation to the phylogenesis of various genera of Actinomycetales].
Bull Soc Chim Biol (Paris). 1967;49(6):695-706 PMID: 4861892

Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.10.1.236-239.1974

Published

1974-07-00

Pages

236-9

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC414983

Subset

External Links

PubMed source DOI: 10.1128/iai.10.1.236-239.1974 PMC Full Text View journal details

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