Determination of the colonization resistance of the digestive tract of individual mice.

The Journal of hygiene ·Vol. 72 ·No. 3 ·1974-06-00 ·Pages 379-87

van der Waaij D, Berghuis JM

Abstract

It has been shown that it is possible to investigate the colonization resistance in individual mice by determining the concentration of a certain contaminant (S.R.-E. coli) in the faeces during the first 4 days after contamination. Experimental contamination is contra-indicated in many cases such as in individuals with decreased resistance to infection. Particularly in this group, the value of the colonization resistance should be determined. It appeared to be possible to determine the colonization resistance in such individuals by quantitative biotyping of the Enterobacteriaceae species in the faeces on several consecutive days.

MeSH Terms

Administration, Oral Animals Bacitracin/administration & dosage Bacteria/pathogenicity Biological Assay Enterobacteriaceae/classification,isolation & purification Escherichia coli/isolation & purification Feces/microbiology Female Intestines/microbiology Mice/radiation effects Natamycin/administration & dosage Neomycin/administration & dosage Radiation Effects Streptomycin/administration & dosage

Chemicals

Bacitracin Natamycin Neomycin Streptomycin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

van der Waaij D

Berghuis J M

References (10)

10 references, click to expand

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Article Info

Journal

The Journal of hygiene

Abbr.

J Hyg (Lond)

ISSN

0022-1724

DOI

10.1017/s0022172400023615

Published

1974-06-00

Pages

379-87

Language

English

Region

England

NLM ID

0375374

PMCID

PMC2130522

Subset

External Links

PubMed source DOI: 10.1017/s0022172400023615 PMC Full Text View journal details

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Determination of the colonization resistance of the digestive tract of individual mice.

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