Selective action of erythromycin on initiating ribosomes.

Binding Sites Carbon Radioisotopes Chromatography, Gel Erythromycin/metabolism,pharmacology Escherichia coli/cytology,metabolism Kinetics Methionine/metabolism Peptide Chain Initiation, Translational/drug effects Peptide Initiation Factors Polyribosomes/drug effects,metabolism Protein Binding RNA, Bacterial/metabolism RNA, Ribosomal/metabolism RNA, Transfer/metabolism Receptors, Drug/drug effects Ribosomes/drug effects,metabolism Spectrophotometry, Ultraviolet Temperature Time Factors Tritium Valine/metabolism

Carbon Radioisotopes Peptide Initiation Factors RNA, Bacterial RNA, Ribosomal Receptors, Drug Tritium Erythromycin RNA, Transfer Methionine Valine