Template specificity of ribonucleic acid polymerase in asporogenous mutants of Bacillus subtilis.

Journal of bacteriology ·Vol. 112 ·No. 3 ·1972-12-00 ·Pages 1270-4

Brevet J, Sonenshein AL

Abstract

Asporogenous mutants of Bacillus subtilis were examined for the change in template specificity of ribonucleic acid (RNA) polymerase characteristic of wild-type cells undergoing sporulation. Mutants blocked at stages II, III, and IV showed a changed specificity of the enzyme after the end of growth and were in this respect indistinguishable from the wild type. The RNA polymerase of eight stage-zero mutants (out of nine tested) which possess mutations that map at six distinct loci retained the template specificity of vegetative cells.

MeSH Terms

Adenosine Triphosphate/metabolism Bacillus subtilis/enzymology,growth & development Cell-Free System Chromosome Mapping Coliphages DNA, Viral DNA-Directed RNA Polymerases/metabolism Genetics, Microbial Mutation Polynucleotides Spores, Bacterial/growth & development Templates, Genetic Time Factors Transcription, Genetic Tritium Uracil Nucleotides/metabolism

Chemicals

DNA, Viral Polynucleotides Uracil Nucleotides Tritium Adenosine Triphosphate DNA-Directed RNA Polymerases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Brevet J

Sonenshein A L

References (12)

12 references, click to expand

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Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.112.3.1270-1274.1972

Published

1972-12-00

Pages

1270-4

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC251558

Subset

External Links

PubMed source DOI: 10.1128/jb.112.3.1270-1274.1972 PMC Full Text View journal details

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Template specificity of ribonucleic acid polymerase in asporogenous mutants of Bacillus subtilis.

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