Glucose tolerance and insulin secretion in patients with chronic duodenal ulcer.

British medical journal ·Vol. 4 ·No. 5837 ·1972-11-18 ·Pages 393-6

Humphrey CS, Dykes JR, Johnston D

Abstract

An oral glucose tolerance test has been used to compare carbohydrate metabolism in patients suffering from chronic duodenal ulceration with that in a matched group of normal subjects. A significantly greater rise in blood glucose concentration was observed in the duodenal ulcer group, and this was associated with a significantly greater output of insulin. The reason for these findings may be an abnormal secretion of one or more of the small-bowel hormones.

MeSH Terms

Adult Blood Glucose/analysis Chronic Disease Duodenal Ulcer/blood,metabolism Female Gastric Juice/metabolism Gastrointestinal Hormones/metabolism Glucose/metabolism Glucose Tolerance Test Humans Insulin/blood,metabolism Insulin Secretion Male Middle Aged Secretory Rate

Chemicals

Blood Glucose Gastrointestinal Hormones Insulin Glucose

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Humphrey C S

Dykes J R

Johnston D

References (34)

34 references, click to expand

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Article Info

Journal

British medical journal

Abbr.

Br Med J

ISSN

0007-1447

DOI

10.1136/bmj.4.5837.393

Published

1972-11-18

Pages

393-6

Language

English

Region

England

NLM ID

0372673

PMCID

PMC1786696

Subset

External Links

PubMed source DOI: 10.1136/bmj.4.5837.393 PMC Full Text

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