Treatment of abrin and ricin with -mercaptoethanol opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell-free system.

Acyltransferases/antagonists & inhibitors Animals Blood Proteins/biosynthesis Carbon Isotopes Cell-Free System Diphtheria Toxin Electrophoresis, Polyacrylamide Gel Kinetics Lethal Dose 50 Leucine/metabolism Macromolecular Substances Mercaptoethanol Mice Oxidation-Reduction Peptide Chain Elongation, Translational Plant Lectins Plants Plants, Toxic Rabbits Reticulocytes/drug effects,metabolism Ricin/pharmacology,toxicity Ricinus Toxins, Biological/pharmacology,toxicity Tritium

Blood Proteins Carbon Isotopes Diphtheria Toxin Macromolecular Substances Plant Lectins Toxins, Biological Tritium Mercaptoethanol Ricin Acyltransferases Leucine