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PMID: 4672513 Published · ppublish English Journal Article

On treating the chromosome as the unit of selection.

Genetics ·Vol. 72 ·No. 1 ·1972-09-00 ·Pages 157-68

Slatkin M

Abstract

A simple method is presented for approximating the behavior of a multiple genetic system under the action of selection and linkage. The effects of genetic drift and mutation are left out. It is found that the results are close to those obtained from a computer simulation of the same problem by Franklin and Lewontin (1970). It is possible to describe the system in terms of a correlation length on the chromosome which measures the degree to which the different parts are bound by linkage. There is also a brief discussion about the higher order correlation coefficients as a measure of the interaction effects.

MeSH Terms
Alleles Chromosomes Female Gene Frequency Genes Genetic Linkage Male Mathematics Models, Biological Ovum Probability Selection, Genetic Spermatozoa
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Slatkin M
References (1)
1 references, click to expand
  1. Is the gene the unit of selection?
    Genetics. 1970 Aug;65(4):707-34 PMID: 5518513
Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
Published
1972-09-00
Pages
157-68
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1212809
Subset
IM
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