Insulin secretion and pancreatic exocrine function in patients with chronic pancreatitis.

Diabetologia ·Vol. 16 ·No. 6 ·1979-06-00 ·Pages 355-8

Kalk WJ, Vinik AI, Jackson WP, Bank S

Abstract

The relationship between insulin responses to oral glucose and pancreatic exocrine function were examined in 15 patients with chronic pancreatitis. Good correlations were found between the insulin responses and exocrine pancreatic function measured as the concentrations of pancreatic enzymes in duodenal juice after intravenous cholecystokinin-pancreazymin (CCK-PZ). There appears to be a roughly parallel loss of endocrine and exocrine function in the course of chronic pancreatitis.

MeSH Terms

Administration, Oral Adult Cholecystokinin/administration & dosage Chronic Disease Duodenum Female Glucose/administration & dosage Humans Injections, Intravenous Insulin/metabolism Insulin Secretion Intestinal Secretions/enzymology Male Middle Aged Pancreas/enzymology,physiopathology Pancreatitis/physiopathology

Chemicals

Insulin Cholecystokinin Glucose

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Kalk W J

Vinik A I

Jackson W P

Bank S

References (14)

14 references, click to expand

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Article Info

Journal

Diabetologia

Abbr.

Diabetologia

ISSN

0012-186X

DOI

10.1007/BF01223154

Published

1979-06-00

Pages

355-8

Language

English

Region

Germany

NLM ID

0006777

Subset

External Links

PubMed source DOI: 10.1007/BF01223154 View journal details

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Insulin secretion and pancreatic exocrine function in patients with chronic pancreatitis.

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