Regulation of pyruvate dehydrogenase in muscle. Inhibition by citrate.

Adenosine Triphosphate/pharmacology Alcohols/pharmacology Animals Calcium/administration & dosage,pharmacology Chelating Agents/pharmacology Citrates Drug Synergism Enzyme Activation/drug effects Fluorine/pharmacology Magnesium/pharmacology Male Mitochondria, Muscle/drug effects,enzymology Multienzyme Complexes/antagonists & inhibitors Muscles/cytology Osmolar Concentration Pyruvate Dehydrogenase Complex/antagonists & inhibitors,metabolism Rats Structure-Activity Relationship Time Factors Tricarboxylic Acids/pharmacology

Alcohols Chelating Agents Citrates Multienzyme Complexes Pyruvate Dehydrogenase Complex Tricarboxylic Acids Fluorine Adenosine Triphosphate Magnesium Calcium