Alteration of 23 S ribosomal RNA and erythromycin-induced resistance to lincomycin and spiramycin in Staphylococcus aureus.

Bacillus/metabolism Bacterial Proteins/biosynthesis Binding Sites Carbon Isotopes Drug Resistance, Microbial Erythromycin/pharmacology Hybridization, Genetic Leucomycins/pharmacology Lincomycin/pharmacology Phenylalanine/metabolism Protein Binding RNA, Bacterial/metabolism RNA, Ribosomal/metabolism Ribosomes/metabolism Species Specificity Staphylococcus/cytology,drug effects,metabolism Time Factors

Bacterial Proteins Carbon Isotopes Leucomycins RNA, Bacterial RNA, Ribosomal Phenylalanine Erythromycin Lincomycin