Home LiteratureArticle Details
PMID: 4741849 Published · ppublish English Journal Article

Hemoglobin Kenya, the product of a gamma-beta fusion gene: studies of the family.

American journal of human genetics ·Vol. 25 ·No. 5 ·1973-09-00 ·Pages 548-63

Kendall AG, Ojwang PJ, Schroeder WA, Huisman TH

Abstract

暂无摘要

MeSH Terms
Adult Amino Acid Sequence Amino Acids/analysis Chromatography, Ion Exchange Crossing Over, Genetic Electrophoresis, Starch Gel Fanconi Syndrome/blood Female Fetal Hemoglobin/analysis Genes Genetics, Medical Hemoglobin, Sickle/analysis Hemoglobins, Abnormal/analysis Heterozygote Humans Infant Kenya Male Pedigree
Chemicals
Amino Acids Hemoglobin, Sickle Hemoglobins, Abnormal Fetal Hemoglobin
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Kendall A G
Ojwang P J
Schroeder W A
Huisman T H
References (23)
23 references, click to expand
  1. An improved gradient for ion exchange chromatography of peptides on Dowex-1.
    Anal Chem. 1965 Nov;37(12):1583-5 PMID: 5828145
  2. Studies on the heterogeneity of hemoglobin. IX. The use of Tris(hydroxymethyl)aminomethanehcl buffers in the anion-exchange chromatography of hemoglobins.
    J Chromatogr. 1965 Jul;19(1):160-9 PMID: 5857919
  3. On the aminoethylation of proteins.
    J Biol Chem. 1966 Aug 10;241(15):3457-61 PMID: 5919679
  4. Haemoglobin A2: alpha-2-delta-2-16 glycine--arginine.
    Nature. 1966 Mar 19;209(5029):1217-8 PMID: 5956309
  5. Structural characterization of two delta chain variants. Hemoglobin A'-2 (B2) and hemoglobin Flatbush.
    J Biol Chem. 1967 Nov 10;242(21):5141-5 PMID: 6058951
  6. Studies on the heterogeneity of hemoglobin. 13. Chromatography of various human and animal hemoglobin types on DEAE-Sephadex.
    J Chromatogr. 1968 Feb 20;32(4):723-7 PMID: 5645562
  7. Separation of the alpha and beta-chains of human hemoglobin.
    Nature. 1968 Jul 6;219(5149):69-70 PMID: 5659619
  8. Qualitative and quantitative studies of sickle cell hemoglobin in homozygotes and heterozygotes.
    Clin Chim Acta. 1968 Dec;22(4):593-601 PMID: 5722343
  9. Evidence for multiple structural genes for the gamma chain of human fetal hemoglobin.
    Proc Natl Acad Sci U S A. 1968 Jun;60(2):537-44 PMID: 5248810
  10. Evidence for multiple structural genes for the gamma-chain of human fetal hemoglobin in hereditary persistence of fetal hemoglobin.
    Ann N Y Acad Sci. 1969 Nov 20;165(1):320-31 PMID: 5260154
  11. Hemoglobin Richmond, a human hemoglobin which forms asymmetric hybrids with other hemoglobins.
    J Biol Chem. 1969 Nov 25;244(22):6105-16 PMID: 4981790
  12. Hemoglobin-Lepore-Baltimore, a third type of a delta, beta crossover (delta 50, beta 86).
    Eur J Biochem. 1969 Sep;10(2):371-6 PMID: 5356627
  13. Heterogeneity of fetal hemoglobin in beta-thalassemia of the Negro.
    Am J Hum Genet. 1970 Sep;22(5):505-14 PMID: 5516235
  14. New aspects of the structure, function, and synthesis of hemoglobins.
    CRC Crit Rev Clin Lab Sci. 1970 Jul;1(3):471-2 PMID: 4938325
  15. Chemical heterogeneity of fetal hemoglobin in subjects with sickle cell anemia, homozygous Hb-C disease, SC disease, and various combinations of hemoglobin variants.
    Clin Chim Acta. 1972 Apr;38(1):5-16 PMID: 5031797
  16. Hemoglobin Lepore Washington in two Jamaican families: interaction with beta chain variants.
    Blood. 1972 Aug;40(2):246-56 PMID: 4625560
  17. Evidence for four nonallelic structural genes for the chain of human fetal hemoglobin.
    Biochem Genet. 1972 Oct;7(2):131-9 PMID: 5050916
  18. Chromatographic separation of hemoglobins A 2 and C. The quantities of hemoglobin A 2 in patients with AC trait, CC disease, and C- -thalassemia.
    Clin Chim Acta. 1972 Aug;40(1):159-63 PMID: 5056624
  19. Normal and abnormal human hemoglobins.
    Adv Clin Chem. 1972;15:149-253 PMID: 4629365
  20. Hemoglobin Kenya, the product of fusion of amd polypeptide chains.
    Arch Biochem Biophys. 1972 Dec;153(2):850-3 PMID: 4676910
  21. The fusion of two peptide chains in hemoglobin Lepore and its interpretation as a genetic deletion.
    Proc Natl Acad Sci U S A. 1962 Nov 15;48:1880-6 PMID: 13968954
  22. THE AMINO ACID SEQUENCE OF THE GAMMA CHAIN OF HUMAN FETAL HEMOGLOBIN.
    Biochemistry. 1963 Sep-Oct;2:992-1008 PMID: 14087393
  23. Estimation of small percentages of foetal haemoglobin.
    Nature. 1959 Dec 12;184(Suppl 24):1877-8 PMID: 13800165
Article Info
Journal
American journal of human genetics
Abbr.
Am J Hum Genet
ISSN
0002-9297
Published
1973-09-00
Pages
548-63
Language
English
Region
United States
NLM ID
0370475
PMCID
PMC1762644
Subset
IM
External Links
PubMed source PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2