Immunologic evidence that staphylococcal alpha toxin is oriented on membranes.

Canadian journal of microbiology ·Vol. 25 ·No. 6 ·1979-06-00 ·Pages 686-92

Lo CY, Fackrell HB

Abstract

Antibodies to staphylococcal alpha toxin were separated into two distinct populations. One population prevented binding of alpha toxin onto erythrocyte membranes. The other population neutralized after the toxin was bound onto erythrocytes and thereby brought about an indirect hemagglutination reaction. The data suggest that alpha toxin has a membrane-binding region.

MeSH Terms

Animals Antibodies, Bacterial Binding Sites, Antibody Erythrocyte Membrane/immunology Erythrocytes/immunology Hemagglutination Tests Hemolysin Proteins/immunology Hot Temperature Humans Neutralization Tests Species Specificity Staphylococcal Toxoid/immunology Staphylococcus aureus/immunology

Chemicals

Antibodies, Bacterial Hemolysin Proteins Staphylococcal Toxoid

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Lo C Y

Fackrell H B

Article Info

Journal

Canadian journal of microbiology

Abbr.

Can J Microbiol

ISSN

0008-4166

DOI

10.1139/m79-099

Published

1979-06-00

Pages

686-92

Language

English

Region

Canada

NLM ID

0372707

Subset

External Links

PubMed source DOI: 10.1139/m79-099 View journal details

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Immunologic evidence that staphylococcal alpha toxin is oriented on membranes.

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