Enzymatic defects in hepatic porphyria. Preliminary observations in patients with porphyria cutanea tarda and variegate porphyria.

5-Aminolevulinate Synthetase/metabolism Carbon Radioisotopes Cytochrome P-450 Enzyme System/metabolism Heme/biosynthesis Humans Iron Liver/enzymology Liver Diseases/enzymology,urine Lyases/metabolism Mitochondria, Muscle/enzymology Muscles/enzymology Porphyrias/enzymology,urine Porphyrins Spectrometry, Fluorescence Spectrophotometry, Ultraviolet Succinates/metabolism Time Factors

Carbon Radioisotopes Porphyrins Succinates Heme Cytochrome P-450 Enzyme System Iron 5-Aminolevulinate Synthetase Lyases