Evidence of an essential histidine residue in thermolysin.

Anhydrides/metabolism,pharmacology Benzyl Compounds/pharmacology Binding Sites Binding, Competitive Drug Stability Enzyme Activation Ethyl Ethers/metabolism,pharmacology Formates/metabolism,pharmacology Histidine/analysis Hydrogen-Ion Concentration Hydroxylamines/pharmacology Kinetics Phenylalanine/pharmacology Spectrophotometry, Ultraviolet Thermolysin/analysis,antagonists & inhibitors,metabolism Tyrosine/metabolism

Anhydrides Benzyl Compounds Ethyl Ethers Formates Hydroxylamines Tyrosine Phenylalanine Histidine Thermolysin