Aminoglycoside resistance in bacteria medicated by gentamicin acetyltransferase II, an enzyme modifying the 2'-amino group of aminoglycoside antibiotics.

Acetyl Coenzyme A/metabolism Acetylation Acetyltransferases/antagonists & inhibitors,metabolism Aminoglycosides/metabolism,pharmacology Anti-Bacterial Agents/metabolism Carbon Radioisotopes Drug Resistance, Microbial Gentamicins/metabolism Hydrogen-Ion Concentration Kanamycin/metabolism Kinetics Mass Spectrometry Neomycin/metabolism Phosphotransferases/metabolism Proteus/enzymology Structure-Activity Relationship

Aminoglycosides Anti-Bacterial Agents Carbon Radioisotopes Gentamicins Kanamycin Acetyl Coenzyme A Acetyltransferases gentamicin 3-acetyltransferase Phosphotransferases Neomycin