Electrophoretic mobility and agglutinability of red blood cells: a "new" polymorphism in mice.

The Journal of experimental medicine ·Vol. 139 ·No. 2 ·1974-02-01 ·Pages 313-22

Rubinstein P, Liu N, Streun EW, Decary F

Abstract

A quantitative method has been developed to determine agglutinability of mouse red blood cells. Tests with different inbred strains of mice revealed only two phenotypes. The same inbred strains were tested with the cytopherometer to determine the electrophoretic mobility of the corresponding red cells. Again, two phenotypes were uncovered, and faster mobility was found in the red cells that had higher agglutinability. The genetic control of this character is autosomal and codominant, and segregates independently of H-2 and coat color.

MeSH Terms

Animals Cell Movement Crosses, Genetic Electrophoresis Erythrocytes/immunology Female Genetic Linkage Hemagglutination Histocompatibility Histocompatibility Antigens Homozygote Hybridization, Genetic Male Mice Mice, Inbred A Mice, Inbred C57BL Mice, Inbred Strains Phenotype Pigmentation Polymorphism, Genetic Sex Factors Species Specificity

Chemicals

Histocompatibility Antigens

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Rubinstein P

Liu N

Streun E W

Decary F

References (11)

11 references, click to expand

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Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.139.2.313

Published

1974-02-01

Pages

313-22

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2139536

Subset

External Links

PubMed source DOI: 10.1084/jem.139.2.313 PMC Full Text View journal details

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Electrophoretic mobility and agglutinability of red blood cells: a "new" polymorphism in mice.

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