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PMID: 4815721 Published · ppublish English Journal Article

Pineal gland: 24-hour rhythm in norepinephrine turnover.

Science (New York, N.Y.) ·Vol. 184 ·No. 4133 ·1974-04-12 ·Pages 163-5

Brownstein M, Axelrod J

Abstract

There is a 24-hour rhythm in the turnover of norepinephrine in sympathetic nerves innervating the pineal gland. This rhythm persists in blinded animals but is suppressed in normnal rats by light. The rhythm in norepinephrine turnover generates the rhythums in pineal indoleamines and N-acetyltransferase.

MeSH Terms
Acetyltransferases/metabolism Animals Circadian Rhythm Darkness Kinetics Light Norepinephrine/metabolism Pineal Gland/innervation,metabolism Rats Receptors, Adrenergic Serotonin/metabolism Sympathetic Nervous System/physiology Tritium
Chemicals
Receptors, Adrenergic Tritium Serotonin Acetyltransferases Norepinephrine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Brownstein M
Axelrod J
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.184.4133.163
Published
1974-04-12
Pages
163-5
Language
English
Region
United States
NLM ID
0404511
Subset
IM
External Links
PubMed source DOI: 10.1126/science.184.4133.163 View journal details
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