The use of new methods to measure: the effect of diet and inducers of microsomal enzyme synthesis on cytochrome P-450 in liver homogenates, and on metabolism of dimethyl nitrosamine.

Animals Benzopyrenes/pharmacology Carbon Monoxide/pharmacology Cytochrome P-450 Enzyme System/metabolism Dealkylation Diet Dietary Fats Dietary Proteins Dimethylamines/metabolism,toxicity Enzyme Induction/drug effects Formaldehyde/analysis In Vitro Techniques Kinetics Liver/metabolism Methods Microsomes, Liver/enzymology Nitrosamines/metabolism,toxicity Oxidation-Reduction Phenobarbital/pharmacology Rats Stimulation, Chemical

Benzopyrenes Dietary Fats Dietary Proteins Dimethylamines Nitrosamines Formaldehyde Carbon Monoxide Cytochrome P-450 Enzyme System Phenobarbital