Home LiteratureArticle Details
PMID: 4823845 Published · ppublish English Journal Article

Energy metabolism in sepsis: treatment based on different patterns in shock and high output stage.

Annals of surgery ·Vol. 179 ·No. 5 ·1974-05-00 ·Pages 684-96

Clowes GH, O'Donnell TF, Ryan NT, Blackburn GL

Abstract

暂无摘要

MeSH Terms
Adult Aged Amino Acids/metabolism Animals Blood Glucose Blood Pressure Body Temperature Central Venous Pressure Dietary Fats/metabolism Energy Metabolism Fasting Female Glucose/metabolism Humans Hypotension/complications Insulin/blood Lactates/blood,metabolism Male Middle Aged Nitrogen/metabolism Oxidation-Reduction Oxygen Consumption Proteins/metabolism Respiratory System/drug effects Sepsis/metabolism Shock, Septic/complications Starvation Swine
Chemicals
Amino Acids Blood Glucose Dietary Fats Insulin Lactates Proteins Glucose Nitrogen
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Clowes G H
O'Donnell T F
Ryan N T
Blackburn G L
References (48)
48 references, click to expand
  1. Cardiovascular stresses in surgery.
    Surg Clin North Am. 1969 Jun;49(3):489-504 PMID: 5769772
  2. Microdetermination of long-chain fatty acids in plasma and tissues.
    J Biol Chem. 1960 Sep;235:2595-9 PMID: 13817286
  3. Relationships of pyruvate and lactate during anaerobic metabolism. II. Exercise and formation of O-debt.
    J Clin Invest. 1958 Feb;37(2):255-63 PMID: 13513756
  4. Contribution of protein to caloric expenditure following injury.
    Surgery. 1970 Jul;68(1):168-74 PMID: 10483465
  5. Regulation of glucose uptake by muscle. 9. Effects of fatty acids and ketone bodies, and of alloxan-diabetes and starvation, on pyruvate metabolism and on lactate-pyruvate and L-glycerol 3-phosphate-dihydroxyacetone phosphate concentration ratios in rat heart and rat diaphragm muscles.
    Biochem J. 1964 Dec;93(3):665-78 PMID: 4284560
  6. Haemodynamic changes resulting from thrombin induced intravascular coagulation.
    Cardiovasc Res. 1970 Oct;4(4):443-51 PMID: 5500125
  7. Carbohydrate metabolism in the baboon subjected to gram-negative (E. coli) septicemia. I. Hyperglycemia with depressed plasma insulin concentrations.
    Ann Surg. 1971 Jul;174(1):91-100 PMID: 4933532
  8. Circulating factors in the etiology of pulmonary insufficiency and right heart failure accompanying severe sepsis (peritonitis).
    Ann Surg. 1970 May;171(5):663-78 PMID: 5441362
  9. Antagonism between the effects of insulin and glucagon on the isolated liver.
    Diabetes. 1969 Nov;18(11):724-32 PMID: 5348515
  10. Pulmonary and circulatory effects of fibrinopeptides.
    Circ Res. 1967 Oct;21(4):469-85 PMID: 6057706
  11. Blood lactic acid levels in irreversible hemorrhagic and lethal endotoxin shock.
    Surg Gynecol Obstet. 1968 Jun;126(6):1247-50 PMID: 5652663
  12. Mechanisms for the high circulatory requirements in sepsis and septic shock.
    Ann Surg. 1969 Oct;170(4):677-95 PMID: 4898969
  13. EFFECT OF FREE FATTY ACIDS ON METABOLISM OF PYRUVIC AND LACTIC ACIDS.
    Am J Physiol. 1965 May;208:887-91 PMID: 14286858
  14. Circulatory and metabolic alterations associated with survival or death in peritonitis: clinical analysis of 25 cases.
    Ann Surg. 1966 Jun;163(6):866-85 PMID: 5933801
  15. Glucagon physiology and pathophysiology.
    N Engl J Med. 1971 Aug 19;285(8):443-9 PMID: 4997492
  16. Regional capillary blood flow and oxygen uptake in severe sepsis.
    Surg Gynecol Obstet. 1971 Apr;132(4):637-44 PMID: 4930019
  17. Effect of insulin on the performance and metabolism of the anoxic isolated perfused rat heart.
    Circ Res. 1973 Jan;32(1):108-16 PMID: 4684123
  18. Metabolism during the postinjury period.
    Adv Clin Chem. 1969;12:1-55 PMID: 4906806
  19. Depression of myocardial contractility in rats by free fatty acids during hypoxia.
    Circ Res. 1970 Apr;26(4):439-49 PMID: 5435707
  20. Observations on the pathogenesis of the pneumonitis associated with severe infections in other parts of the body.
    Ann Surg. 1968 May;167(5):630-50 PMID: 4869050
  21. Measurement of blood flow and volume in the forearm of man; with notes on the theory of indicator-dilution and on production of turbulence, hemolysis, and vasodilatation by intra-vascular injection.
    J Clin Invest. 1954 Apr;33(4):482-504 PMID: 13152188
  22. Peripheral intravenous feeding with isotonic amino acid solutions.
    Am J Surg. 1973 Apr;125(4):447-54 PMID: 4632601
  23. Critical variables in the radioimmunoassay of serum insulin using the double antibody technic.
    Diabetes. 1965 Dec;14(12):771-9 PMID: 5850216
  24. Blood sugar and insulin response of humans in shock.
    Ann Surg. 1970 Sep;172(3):342-50 PMID: 5459093
  25. The Banting Memorial Lecture 1971. Physiology of insulin in man.
    Diabetes. 1971 Dec;20(12):785-99 PMID: 4941092
  26. Direct measurement of insulin secretory rate: studies in shocked primates and postoperative patients.
    Ann Surg. 1972 Sep;176(3):296-304 PMID: 4627397
  27. Protein sparing therapy during periods of starvation with sepsis of trauma.
    Ann Surg. 1973 May;177(5):588-94 PMID: 4634108
  28. Abnormal vascular tone, defective oxygen transport and myocardial failure in human septic shock.
    Ann Surg. 1967 Apr;165(4):504-17 PMID: 6021451
  29. Low output syndrome. Recognition and treatment.
    J Thorac Cardiovasc Surg. 1969 Jan;57(1):138-50 PMID: 5762575
  30. The quantitatively minor role of carbohydrate in oxidative metabolism by skeletal muscle in intact man in the basal state; measurements of oxygen and glucose uptake and carbon dioxide and lactate production in the forearm.
    J Clin Invest. 1956 Jun;35(6):671-82 PMID: 13319506
  31. The role of insulin and glucagon in acute trauma.
    Surg Forum. 1973;24:97-8 PMID: 4806108
  32. Localization of the energy pathway block in shock.
    Surgery. 1968 Jul;64(1):55-9 PMID: 5658740
  33. Abnormal pancreatic alpha-cell function in bacterial infections.
    N Engl J Med. 1973 Apr 5;288(14):700-3 PMID: 4569497
  34. The affinity of hemoglobin for oxygen: its control and in vivo significance.
    Surgery. 1970 Jul;68(1):187-94; discussion 194-5 PMID: 10483468
  35. Determination of cardiac output by equating venous return curves with cardiac response curves.
    Physiol Rev. 1955 Jan;35(1):123-9 PMID: 14356924
  36. Whole body and splanchnic blood flow and oxygen consumption measurements in patients with intraperitoneal infection.
    Ann Surg. 1970 Mar;171(3):321-8 PMID: 4907235
  37. A receptor mechanism for the inhibition of insulin release by epinephrine in man.
    J Clin Invest. 1967 Jan;46(1):86-94 PMID: 6018752
  38. Human forearm metabolism during progressive starvation.
    J Clin Invest. 1971 Jul;50(7):1536-45 PMID: 5090067
  39. Blood-borne humoral factors in the pathophysiology of circulatory shock.
    Circ Res. 1973 Feb;32(2):129-39 PMID: 4405538
  40. Carbohydrate metabolism in man: effect of elective operations and major injury.
    J Appl Physiol. 1971 Jul;31(1):110-6 PMID: 5556946
  41. Studies of the absorption and metabolism of glucose following injury; the systemic response to injury.
    Ann Surg. 1955 Mar;141(3):321-6 PMID: 14350571
  42. Defective oxygen consumption in septic shock.
    Surg Gynecol Obstet. 1969 May;128(5):1051-60 PMID: 5813624
  43. Physiologic patterns in surviving and nonsurviving shock patients. Use of sequential cardiorespiratory variables in defining criteria for therapeutic goals and early warning of death.
    Arch Surg. 1973 May;106(5):630-6 PMID: 4701410
  44. Glucagon and the insulin: glucagon ratio in diabetes and other catabolic illnesses.
    Diabetes. 1971 Dec;20(12):834-8 PMID: 5120326
  45. Patterns of septic shock in man--a detailed study of 56 patients.
    Ann Surg. 1967 Oct;166(4):543-62 PMID: 6061542
  46. PROTEIN METABOLISM AFTER INJURY.
    Metabolism. 1963 Sep;12:783-9 PMID: 14062760
  47. Myocardial effects of intestinal ischemia.
    J Surg Res. 1969 May;9(5):319-23 PMID: 5780594
  48. Starvation in man.
    N Engl J Med. 1970 Mar 19;282(12):668-75 PMID: 4915800
Article Info
Journal
Annals of surgery
Abbr.
Ann Surg
ISSN
0003-4932
DOI
10.1097/00000658-197405000-00023
Published
1974-05-00
Pages
684-96
Language
English
Region
United States
NLM ID
0372354
PMCID
PMC1356054
Subset
IM
External Links
PubMed source DOI: 10.1097/00000658-197405000-00023 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2