Interactions between mammalian cell DNA and inorganic platinum compounds. II. Interstrand cross-linking of isolated and cellular DNA by platinum(IV) compounds.

Alkylating Agents/pharmacology Bromodeoxyuridine/pharmacology Cell Nucleus/metabolism Cell Survival Cisplatin/metabolism,pharmacology,toxicity Culture Media Cytoplasm/metabolism DNA/metabolism DNA, Neoplasm/metabolism Dimethyl Sulfoxide HeLa Cells/drug effects Humans Isomerism Macromolecular Substances Molecular Weight Neoplasm Proteins/metabolism Protein Binding Proteins/metabolism RNA/metabolism RNA, Neoplasm/metabolism Structure-Activity Relationship Thymidine/metabolism Tritium

Alkylating Agents Culture Media DNA, Neoplasm Macromolecular Substances Neoplasm Proteins Proteins RNA, Neoplasm Tritium RNA DNA Bromodeoxyuridine Cisplatin Thymidine Dimethyl Sulfoxide