Immediate hypersensitivity responses in flatfish.

Science (New York, N.Y.) ·Vol. 185 ·No. 4148 ·1974-07-26 ·Pages 360-1

Fletcher TC, Baldo BA

Abstract

Fungal extracts that precipitate with human C-reactive protein caused immediate erythema on subdermal injection into marine flatfish. Only species with calcium-dependent serum precipitins to these fungi showed skin reactions. Immediate hypersensitivity in a nonreactive species could be induced after injection with serum from reactive species. The transferable serum factor (or factors) was heat sensitive.

MeSH Terms

Allergens Animals Antibodies, Fungal Antigens, Fungal C-Reactive Protein Cross Reactions Fishes/immunology Fungi/immunology Hot Temperature Hypersensitivity, Immediate/immunology Immunization, Passive Immunoglobulin E Passive Cutaneous Anaphylaxis Precipitins Skin Tests Species Specificity

Chemicals

Allergens Antibodies, Fungal Antigens, Fungal Precipitins Immunoglobulin E C-Reactive Protein

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Fletcher T C

Baldo B A

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.185.4148.360

Published

1974-07-26

Pages

360-1

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.185.4148.360 View journal details

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