Regulation of pyruvate-dehydrogenase interconversion in rat-liver mitochondria as related to the phosphorylation state of intramitochondrial adenine nucleotides.

Adenine Nucleotides/metabolism Adenosine Diphosphate/metabolism Adenosine Monophosphate/metabolism Adenosine Triphosphate/metabolism Animals Calcium/pharmacology Chlorobenzenes/pharmacology Energy Metabolism Enzyme Activation/drug effects Glucose/pharmacology Hexokinase/pharmacology Hydrazones/pharmacology In Vitro Techniques Ketoglutaric Acids/metabolism,pharmacology Kinetics Male Mitochondria, Liver/enzymology,metabolism Models, Chemical Oxidative Phosphorylation Pyruvate Dehydrogenase Complex/antagonists & inhibitors,metabolism Pyruvates/metabolism Rats Rotenone/pharmacology Uncoupling Agents/pharmacology

Adenine Nucleotides Chlorobenzenes Hydrazones Ketoglutaric Acids Pyruvate Dehydrogenase Complex Pyruvates Uncoupling Agents Rotenone Adenosine Monophosphate Adenosine Diphosphate Adenosine Triphosphate Hexokinase Glucose Calcium