Catalysis by chymotrypsinogen. Demonstration of an acyl-zymogen intermediate.

Acylation Animals Benzoates/metabolism Binding Sites Binding, Competitive Carbon Radioisotopes Catalysis Cattle Chymotrypsin/metabolism Chymotrypsinogen/analysis,antagonists & inhibitors,metabolism Circular Dichroism Enzyme Activation Guanidines/metabolism Hydrogen-Ion Concentration Isoflurophate/metabolism Kinetics Nitrobenzenes/metabolism Organophosphorus Compounds Propionates Spectrophotometry, Ultraviolet Structure-Activity Relationship Swine Trypsinogen/antagonists & inhibitors

Benzoates Carbon Radioisotopes Guanidines Nitrobenzenes Organophosphorus Compounds Propionates Isoflurophate Trypsinogen Chymotrypsinogen Chymotrypsin