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PMID: 486102 Published · ppublish English Journal Article

Antigen- or mitogen-provoked spleen cells produce factors that stimulate the secretion of macrophages of a neutral proteinase degrading cartilage proteoglycans.

The Biochemical journal ·Vol. 180 ·No. 1 ·1979-04-15 ·Pages 249-51

Hauser P, Vaes G

Abstract

Soluble products released by rabbit spleen cells on stimulation with either mitogen or antigen markedly stimulate the secretion of a proteoglycan-degrading neutral proteinase by rabbit bone-marrow macrophages.

MeSH Terms
Animals Antigens Bone Marrow/enzymology In Vitro Techniques Macrophages/drug effects,enzymology Male Mitogens/pharmacology Peptide Hydrolases/metabolism Proteoglycans/metabolism Rabbits Spleen/cytology,drug effects
Chemicals
Antigens Mitogens Proteoglycans Peptide Hydrolases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Hauser P
Vaes G
References (13)
13 references, click to expand
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Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/bj1800249
Published
1979-04-15
Pages
249-51
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1161042
Subset
IM
External Links
PubMed source DOI: 10.1042/bj1800249 PMC Full Text View journal details
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